LEVORAG emulgel

Medical device for the treatment of anal fissures

Plant-based LevoRag acts as an emollient and lubricant and covers anal microlesions by creating a protective film, thus ensuring the targeted effect of medicinal oils of the sweet almond tree, borage, and extracts of forest mallow, calendula, licorice, and hibiscus. By combining these carefully selected ingredients, it acts together with the antioxidant[2] and immunostimulating properties of tocopherol (vitamin E) and carboxymethyl beta-glucan[3], panthenol.

LevoRag:

  • significantly reduces pain[4], which is very intense in fissures[5];
  • soothes and protects the lesion area during defecation and prevents the formation of new fissures[1];
  • improves vitality, social activities and mental health[4]
  • reduces pain during defecation, accelerates re-epithelialization and fissure healing [5];
  • restores physiological function and reduces spasm.

LevoRag does not contain nitroglycerin, corticosteroids, lidocaine, nickel, artificial colors or fragrances.

LevoRag package is a single-dose tube with an applicator. Each box contains 20 separate doses,

When used twice a day, LevoRag lasts at least 20 days.

Link: http://www.levorag.com/en/

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[1] Uputstvo za upotrebu LevoRag emulgel za lečenje analnih fisura.
[2] Shimizu K. et al. Lipids. 2001 Dec; 36(12):1321-6: Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties.
[3] Marciane Magnani et al. Genet Mol Biol. 2011 Jan-Mar; 34(1): 131-135: Protective effect of carboxymethyl-glucan (CM-G) against DNA damage in patients with advanced prostate cancer.
[4] M. León Arellano et al. Cir Esp. 2014;92(Espec Congr):716: RESULTADOS DE LA ENCUESTA DE SATISFACCIÓN REALIZADA A PACIENTES. CON FISURA ANAL TRATADOS DE FORMA CONSERVADORA
[5] R. Digennaro et al. Tech Coloproctol (2015) 19:287-292: Prospective multicenter observational trial on the safety and efficacy of LEVORAG Emulgel in the treatment of acute and chronic anal fissure.